Career Bioinformatician or Computational Biologist (f/m/d) Bioinformatician or Computational Biologist (f/m/d) Contact VERAXA Biotech GmbHMeyerhofstrasse 169117 HeidelbergCarl-Friedrich-Gauß-Ring 569124 Heidelberg Apply for the job Your tasksBioinformatic analysis of NGS datasets with focus on the identification of immunoglobulin sequences in therapeutic antibody discovery projectsDesigning and performing data analysis workflowsSetup and administration of the required infrastructureInvestigating and integrating developments in NGS technology and data analysis methodsSupport our R&D team in providing analysis and data-driven bioinformatic servicesContribute with your experience to an interdisciplinary team to develop innovative solutionsPrerequisitesPhD in bioinformatics or computational biology with at least one year of Postdoc or industry experience; alternatively, university degree with five years of professional experienceExtensive experience in computational analysis of NGS datasetsAdvanced data analysis skills with R/bioconductor and/or PythonWorking in a Unix environment and ability to administrate itExperience in Bash scripting and workflow development using workflow managers (e.g. Snakemake, Nextflow)Working knowledge of Conda and containerizationA big plus is experience in Ig/TcR sequence reconstruction i.e. Ig-SeqExperience in single cell analysis (e.g., 10X, Drop-seq) is beneficialAbility to independently administrate required infrastructureExperience in working with Cloud solutions would be a plusPleasure to work in an interdisciplinary team on applied research-specific issues and in creative problem solvingFluency in English, since English is a working language in our companyAbout VERAXA BiotechVERAXA Biotech GmbH is a leader in the rapid and functional screening of antibodies using droplet-based microfluidic technology. Compared to current antibody screening methods, VERAXA’s technology enables the quantitative and rapid recognition of antibody functions in target cells for the first time. Together with its proprietary capacities in antibody modifications via ultra-fast and site-specific click chemistry-based drug conjugation, the company will contribute to a significant shortening of preclinical development times for therapeutic antibodies and allow patients to be treated earlier. Senior Scientist Screening (f/m/d) Senior Scientist Screening (f/m/d) Contact VERAXA Biotech GmbHMeyerhofstrasse 169117 HeidelbergCarl-Friedrich-Gauß-Ring 569124 Heidelberg Apply for the job Your responsibilitiesSupport of the department Screening & Development in all operational and technical tasks and execution of screening experiments in own responsibilityImplementation of molecular biological methods for the generation and validation of new fluorescent reporter cell linesIndependent planning/implementation of processes to improve biologic/apparative sensitivity and reliability of screening roundsDevelopment and optimization of cell-based assays and transfer into a microfluidic formatAnalyzing current scientific literature to help identify new targets or new strategies for existing targetsEvaluation and documentation of test resultsSolid know-how in GPCR and/or ion channel related physiology, their related pathologies and existing pharmacological developmentsConceptualize, design, and perform novel in vitro functional assays with primary human and mouse cells for target validationYour qualification & expertisePhD degree in Biology, Biochemistry, Pharmacology or related field with a minimum of 3 years of postdoctoral or equivalent industrial experienceExcellent knowledge of antibody screening, development and engineering in relation to immunology-based diseases and treatment optionsDirect experience with a broad range of immunological techniques, including isolation and stimulation of primary immune cells (of human and rodent origin), multi-color flow cytometry, immune cell-based assay developmentSolid knowledge and hands-on experience in microfluidic technology is an advantage but not absolutely requiredProven track record in supervision of technicians / associates/ traineesHighly motivated and self-driven with excellent communication and presentation skills, capable to work both as a manager and also as a team playerFluency in English (written and oral)About VERAXA BiotechVERAXA Biotech GmbH is a leader in the rapid and functional screening of antibodies using droplet-based microfluidic technology. Compared to current antibody screening methods, VERAXA’s technology enables the quantitative and rapid recognition of antibody functions in target cells for the first time. Together with its proprietary capacities in antibody modifications via ultra-fast and site-specific click chemistry-based drug conjugation, the company will contribute to a significant shortening of preclinical development times for therapeutic antibodies and allow patients to be treated earlier. Senior Scientist ADC engineering (f/m/d) Senior Scientist ADC engineering (f/m/d) Contact VERAXA Biotech GmbHMeyerhofstrasse 169117 HeidelbergCarl-Friedrich-Gauß-Ring 569124 Heidelberg Apply for the job Your tasksOptimization of antibody expression in mammalian cells particularly in suspension cellsOptimization of antibody purificationDevelopment and optimization of cytotoxicity assays in diverse mammalian cell linesSupport of the development and optimization of generating stable cell linesSupport of the screening and selection of gene libraries as well as performing cellular assaysAnalyzing current scientific literature in work related fieldsIndependent planning and realization of experimentsIndependent evaluation and documentation of test resultsPrerequisitesPhD degree in Biology, Biochemistry, Biotechnology or related fields with a minimum of 3 years of postdoctoral or equivalent industrial experienceExcellent knowledge of molecular biology and biochemical methodsDirect experience handling of mammalian cells is required, knowledge in suspension cell culture would be a plusHands-on experience in generating stable cell lines would be advantageous but not requiredWillingness to perform fluorescence flow cytometryProven track record in supervision of technicians / associates/ traineesHighly motivated and self-driven with excellent communication and presentation skills, capable to work as a team playerFluency in English (written and oral)Safe handling of MS OfficeAbout VERAXA BiotechVERAXA Biotech GmbH is a leader in the rapid and functional screening of antibodies using droplet-based microfluidic technology. Compared to current antibody screening methods, VERAXA’s technology enables the quantitative and rapid recognition of antibody functions in target cells for the first time. Together with its proprietary capacities in antibody modifications via ultra-fast and site-specific click chemistry-based drug conjugation, the company will contribute to a significant shortening of preclinical development times for therapeutic antibodies and allow patients to be treated earlier. Scientist Antibody Development (f/m/d) Scientist Antibody Development (f/m/d) Contact VERAXA Biotech GmbHMeyerhofstrasse 169117 HeidelbergCarl-Friedrich-Gauß-Ring 569124 Heidelberg Apply for the job Your responsibilitiesWork as part of the Antibody Development Team on the identification and engineering of potential therapeutic antibody candidatesDesign, perform and analyze functional assays for antibody characterization, either independently or in collaboration with the teamAnalyze antibody sequences and design strategies for sequence optimizationAdministration of an antibody sequences databaseDocumentation and presentation of data to colleagues or partnersOrganize, support and collaborate with other team members to meet project deliverables and timelinesYour qualification & expertisePhD degree in a relevant field preferrable complemented by post-doc or industry experienceHands-on experience in the characterization (incl. assay development) and engineering (incl. humanization) of antibodiesKnowledge of antibody sequence analysis and databasesBackground on humanized mouse models or mammalian display technologies for antibody discovery is a plusHighly motivated and self-driven team player with excellent communication and presentation skillsPleasure, commitment and curiosity to collaboratively work in the creative environment of a young companyFluency in English (written and oral)About VERAXA BiotechVERAXA Biotech GmbH is a leader in the rapid and functional screening of antibodies using droplet-based microfluidic technology. Compared to current antibody screening methods, VERAXA’s technology enables the quantitative and rapid recognition of antibody functions in target cells for the first time. Together with its proprietary capacities in antibody modifications via ultra-fast and site-specific click chemistry-based drug conjugation, the company will contribute to a significant shortening of preclinical development times for therapeutic antibodies and allow patients to be treated earlier. Scientific assistants / Technical assistants / BTAs (f/m/d) Scientific assistants / Technical assistants / BTAs (f/m/d) Contact VERAXA Biotech GmbHMeyerhofstrasse 169117 HeidelbergCarl-Friedrich-Gauß-Ring 569124 Heidelberg Apply for the job Your tasksSupport of generating new antibody constructs by molecular biology methods including handling of bacterial cellsSupport and optimization of antibody expression and purification out of mammalian cellsSupport and optimization of gene library screening and selection proceduresSupport and optimization of cytotoxicity assaysSupport of cultivating diverse mammalian cell linesIndependent evaluation and documentation of test resultsPrerequisitesCompleted training as BTA/Biology Laboratory Technician (m/f) with professional experience or Master’s degree in the field of life scienceHands-on experience in molecular biology techniques (e.g. handling bacterial cells, cloning, DNA preparation)Practical knowledge in the expression and purification of proteinsPractical experience in the production of antibodies out of suspension mammalian cell culture would be advantageousWillingness to perform cytotoxicity studies in diverse mammalian cells would be a plus.Organizational skills, motivated and team-oriented mindsetPleasure, commitment and interest in working on applied and research-specific issues in a teamGood knowledge of English, since English is a working language in our company, andSafe handling of MS OfficeAbout VERAXA BiotechVERAXA Biotech GmbH is a leader in the rapid and functional screening of antibodies using droplet-based microfluidic technology. Compared to current antibody screening methods, VERAXA’s technology enables the quantitative and rapid recognition of antibody functions in target cells for the first time. Together with its proprietary capacities in antibody modifications via ultra-fast and site-specific click chemistry-based drug conjugation, the company will contribute to a significant shortening of preclinical development times for therapeutic antibodies and allow patients to be treated earlier. Project Manager (f/m/d) Project Manager (f/m/d) Contact VERAXA Biotech GmbHMeyerhofstrasse 169117 HeidelbergCarl-Friedrich-Gauß-Ring 569124 Heidelberg Apply for the job Your tasksResponsible for setting-up, monitoring and management of assigned projects (including internal development projects, as well as client related project management activities) from initiation through completion conduct with a primary focus on milestone achievementsDevelop full scale integrated project plansResponsible for tracking of project milestones, timelines and budgetSecures required resources and uses formal processes and tools to manage resources, budget, risks and changesCarries out operational project controlling regarding time, quality and budgetGenerate transparency of the projects ensuring routine reporting to the RDOCLead and co-ordination of virtual project teams cross sitesResponsible for management of external stakeholder and aligning with project operational activitiesPrerequisites & qualificationsDegree/background in natural sciences (FH, University etc.)Qualification in PM or proven track record in PMSeveral years of work experience in project management in the life science environment, preferably in antibody or HTS developmentDetail-oriented and accurate working styleVery good communication and computer skills (i.e. Excel, MS Project, etc.)Fluent EnglishAble to work in a team as well as independentlyAble and used to work under time pressure on multiple projects in a fast changing environmentAbout VERAXA BiotechVERAXA Biotech GmbH is a leader in the rapid and functional screening of antibodies using droplet-based microfluidic technology. Compared to current antibody screening methods, VERAXA’s technology enables the quantitative and rapid recognition of antibody functions in target cells for the first time. Together with its proprietary capacities in antibody modifications via ultra-fast and site-specific click chemistry-based drug conjugation, the company will contribute to a significant shortening of preclinical development times for therapeutic antibodies and allow patients to be treated earlier. Junior Business Development Manager (f/m/d) Junior Business Development Manager (f/m/d) Contact VERAXA Biotech GmbHMeyerhofstrasse 169117 HeidelbergCarl-Friedrich-Gauß-Ring 569124 Heidelberg Apply for the job Your responsibilitiesReporting to the Head of Business Development, you autonomously and successfully lead and maintain customer projects from initiation to contract executionIdentification and development of additional value-adding opportunities offered by Velabs’ antibody generation expertise and proprietary technology platformLead a cross-functional team to facilitate the deal-making processParticipate at scientific and business-related venues (e.g. conferences, partnering-events) and attract new customers for VelabsUnderstand customer’s needs and challenges in order to identify new areas of value creation for VERAXA’s technology platformYour qualification/expertiseBachelor’s or master’s degree in Biology, Biochemistry, Pharmacology or related fieldProfound understanding of antibody biology and strong interest in commercial aspectsAbility to quickly come to grips with new technologies and drug development strategiesBuilding and maintaining senior-level relationships at customer organizationsExperience leading and working on multiple projects collaboratively in a multi-disciplinary team and across multiple functional areasStrategic thinker and self-starter, willingness to travelVery good English communication skills (verbally and in writing) with capability to lead negotiations, German language skills are an assetAbout VERAXA BiotechVERAXA Biotech GmbH is a leader in the rapid and functional screening of antibodies using droplet-based microfluidic technology. Compared to current antibody screening methods, VERAXA’s technology enables the quantitative and rapid recognition of antibody functions in target cells for the first time. Together with its proprietary capacities in antibody modifications via ultra-fast and site-specific click chemistry-based drug conjugation, the company will contribute to a significant shortening of preclinical development times for therapeutic antibodies and allow patients to be treated earlier. Research Scientist in field of immunology (f/m/d) Research Scientist in field of immunology (f/m/d) Contact VERAXA Biotech GmbHMeyerhofstrasse 169117 HeidelbergCarl-Friedrich-Gauß-Ring 569124 Heidelberg Apply for the job Your tasksPlanning and supervision of mouse immunization experimentsSupport of the department of Screening in all operational and technical tasksImplementation of molecular biological methods for the generation and validation of new reporter cell linesConceptualization, design, and performing of novel in vitro functional assays with primary human and mouse cells for target validationValidation and optimization of cell-based assay for the detection of antibody-mediated interaction with cell receptorsTransfer of functional cell assays into a microfluidic formatAnalyzing current scientific literature to help identify new targets or new strategies for existing targetsEvaluation and documentation of test resultsPrerequisitesPhD degree in Immunology, Biology, Pharmacology or related field with a minimum of 3 years of laboratory experienceKnowledge of antibody function and biology in relation to immunology-based treatment options is highly desiredDirect experience with a broad range of immunological techniques, including isolation and stimulation of primary immune cells (of human and rodent origin), multi-color flow cytometry, immune cell-based assay developmentExperience in supervision of technicians / associates/ traineesHighly motivated and self-driven with excellent communication and presentation skillsCapable to work both as a manager and also as a team playerBackground in pharmacology would be a plusAbility to integrate and work in an interdisciplinary teamPleasure, commitment and interest in working on applied and research-specific issuesFluency in English (written and oral)About VERAXA BiotechVERAXA Biotech GmbH is a leader in the rapid and functional screening of antibodies using droplet-based microfluidic technology. Compared to current antibody screening methods, VERAXA’s technology enables the quantitative and rapid recognition of antibody functions in target cells for the first time. Together with its proprietary capacities in antibody modifications via ultra-fast and site-specific click chemistry-based drug conjugation, the company will contribute to a significant shortening of preclinical development times for therapeutic antibodies and allow patients to be treated earlier. Research Associates Biology (f/m/d) Scientific assistants, Technical assistants, BTAs (m/f/d) Contact VERAXA Biotech GmbHMeyerhofstrasse 169117 HeidelbergCarl-Friedrich-Gauß-Ring 569124 Heidelberg Apply for the job Your tasksSupport of the Screening & Development department in all operational and technical tasksImplementation of methods for the generation and validation of new fluorescent reporter cell linesIndependent planning and establishment of cellular reporter assaysSupport and optimization of microfluidic screening experimentsSupport of planning of immunizationsIsolation and handling of cells from animal tissues/organsEvaluation and documentation of test resultsPrerequisitesMaster’s degree in the field of life science or completed training as BTA/Biology Laboratory Technician (m/f/d) with professional experienceHands-on experience in the development of cellular and immunological assays (FACS, ELISA,…)Practical knowledge in the application of protein chemical and molecular biological methodsExperience in antibody development, NGS or virology/microbiology would be a plusWillingness to work with mammalian biological samples. Practical experience in immunization of mice and handling of experimental animals under regulatory aspects (FELASA or similar) is advantageousOrganizational skills, motivated and team-oriented mindsetPleasure, commitment and interest in working on applied and research-specific issues in a teamGood knowledge of English, since English is a working language in our company, andSafe handling of MS OfficeAbout VERAXA BiotechVERAXA Biotech GmbH is a leader in the rapid and functional screening of antibodies using droplet-based microfluidic technology. Compared to current antibody screening methods, VERAXA’s technology enables the quantitative and rapid recognition of antibody functions in target cells for the first time. Together with its proprietary capacities in antibody modifications via ultra-fast and site-specific click chemistry-based drug conjugation, the company will contribute to a significant shortening of preclinical development times for therapeutic antibodies and allow patients to be treated earlier.